Chronopharmacology of antimicrobial agents.
نویسندگان
چکیده
منابع مشابه
Antimicrobial Agents
Use of substances with antimicrobial properties is known to have been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. More recently, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism for some bacteria and discussed the merits of controlling these interactions in medicine. ...
متن کاملAntimicrobial Agents
INTRODUCTION................................................................. 13 PRECLINICAL TESTING STAGES ................................................................. 13 Discovery of New Antibiotics ................................................................. 13 Establishment of SAR ................................................................. 15 Animal Models for Studying the P...
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The f r a c t i o n a l d i s t r i b u t i o n o f l y m p h o c y t e subsets was d e t e r m i n e d i n t h r e e m a l e s u b j e c t s . I t s c o n t r i b u t i o n t o t h e c i r c a d i a n v a r i a t i o n i n t h e exp r ess i on o f ß2~adrenoceptor s i t e s on pe r iphera l m o n o n u c l e a r l e u c o c y t e s ( M N L ) was c a l c u l a t e d t o be 92 .7 -107 .3 % o f t ...
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The pharmacokinetics of apalcillin and piperacillin, each administered intravenously as a single 2-g dose, were compared in 10 volunteers in a randomized study of crossover design using bioassay and high-pressure liquid chromatographic procedures. The concentrations of both penicillins in serum were determined over a period of 12 h and in urine over 24 h. Concentrations of apalcillin and pipera...
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Among gram-negative bacilli isolated from burn wound cultures, some strains of Enterobacteriaceae were resistant to tobramycin (minimal inhibitory concentration [MIC ]> 20 ,g/ml) but susceptible to gentamicin (MIC < 5 ,gg/ml). One Klebsiella pneumoniae and two Enterobacter cloacae strains were selected for studies on their mechanisms of resistance to aminoglycoside antibiotics. Resistance to hi...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1998
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.29.549